Relative Stability of cis- and trans-Hydrindanones

The relative stabilities of several cis- and trans-hydrindanones were compared using both isomerization experiments and MM2 ut solution gel for cats calculations.The generally believed rule that cis-hydrindanones are more depileve easy clean stable than trans-isomers is applicable, but is not always true.This review introduces examples, mainly from studies in our laboratory, to explain these facts.